INSIGHTS

WEEKLY COMPANY INSIGHT: 3M

Roy Davidson, 4 April 2019

CSL140319 

Description

CSL is a leading Australian biopharmaceutical company. It primarily manufactures therapies derived from human blood plasma which are used to treat immune deficiencies, bleeding disorders, trauma, and a range of other diseases. The vast majority of revenues are derived outside Australia.

CSL comprises CSL Behring and Seqirus

CSL Behring accounts for the bulk of CSL’s revenues and earnings and is a global leader in plasma derived and recombinant (lab engineered) products. CSL Behring’s main products are immunoglobulins used to treat immune deficiencies, clotting agents used to treat bleeding disorders such as Haemophilia, and a large number of other plasma derived products used to treat a range of rare diseases, alongside trauma, shock, and severe burns. Biotherapies are produced at facilities in Australia, Germany, the US and Switzerland, and plasma is sourced via a network of collection centres in the US and Germany. Seqirus, previously named bioCSL, manufactures vaccines, pharmaceuticals and antivenoms. Following the acquisition of Novartis’ flu vaccine business, CSL is now the second largest flu vaccine manufacturer in the world.

Research and development provides future opportunities

The company has a strong R&D capacity and spends around 10% of its revenue on R&D each year, ensuring CSL is able to bring innovative products into what can be competitive markets. CSL’s R&D pipeline is currently very healthy with a number of products which can make sizeable contributions. This includes a therapy which could help avoid the onset of a second heart attack (the largest area of health spending globally), and work in using existing products to improve the success rate of transplanted organs.

Broad based growth drivers

Following a period of investment, we see CSL as well positioned; its core products continue to see strong demand, it has a significant research and development pipeline, and has launched several new therapies (Haegarda, Idelvion) which have grown rapidly to become the standard of care in their respective fields. We see CSL’s growth drivers as well balanced across all its business segments, meaning the company is not overly reliant on any one product.

Positive long-term outlook

CSL is a high quality business and the company has in place very efficient infrastructure for the collection and processing (fractionation) of blood into complex biopharmaceutical products. CSL has demonstrated an ability to launch new products, and has several strong products on the market and in its pipeline. The underlying demand for the end-markets the company serves continue to expand with increased rates of diagnosis for rare diseases and emerging market demand.

Risks

  1. safety issue with key product
  2. manufacturing issues
  3. increased competition
Top